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Automated · Label-free · Inside Your Incubator

Time-Lapse Cell Imaging — Continuous, Automated, Unattended

Capture every moment of cell behavior — migration, division, morphology changes — with automated time-lapse imaging inside your CO₂ incubator. 24 wells in parallel. Images every 5 minutes. No manual timepoints. No incubator disruption.

Buchen Sie Ihre kostenfreie Vorführung Scratch Assay Protocol
5 Minuten
Minimum imaging interval
24
Wells simultaneously
14 days
Maximum experiment duration
5 MP
Brightfield resolution
zenCELL owl Time-Lapse · Brightfield · 24-channel
Scratch Assay Time-Lapse
Cell Migration 48h
Spheroid Growth
What is Time-Lapse Cell Imaging?

Capture Cell Dynamics Over Time — Not Just Snapshots

Time-lapse cell imaging captures sequential brightfield images of living cells at defined intervals — from minutes to hours — over the course of an entire experiment. The result is a continuous kinetic dataset that reveals cellular dynamics invisible to endpoint assays.

Unlike conventional microscopy that requires removing cells from the incubator, zenCELL owl captures time-lapse sequences automatically inside your CO₂ incubator — without disrupting temperature, humidity or gas exchange.

  • Wound closure kinetics — full gap closure curve, not just T0 and T24
  • Cell division events captured in real time
  • Morphology changes during drug treatment — onset, peak, recovery
  • Spheroid growth curves over days without incubator disruption
  • Contamination detected early — before the experiment is lost
  • Export as AVI time-lapse video, PNG stack, or CSV kinetic data
See Time-Lapse Live →
Wie es funktioniert

From Setup to Publikationsfertige Daten

1
Place zenCELL owl in Incubator
1.5 kg · 18×18×10 cm · fits any CO₂ incubator shelf. One USB-C cable to your PC. No installation required.
2
Configure Time-Lapse Experiment
Set imaging interval (5 min – 24h), experiment duration (up to 14 days), and select wells. AI autofocus calibrates automatically.
3
Automated Imaging Runs Unattended
zenCELL owl captures brightfield images of all 24 wells at every interval. Monitor remotely from any device, anywhere.
4
Export & Analyze
AVI time-lapse video, PNG image stack, CSV kinetic data. Full ImageJ integration. Publication-ready output.
Validated Applications

What You Can Study with Time-Lapse Imaging

All validated across published research. Label-free. Brightfield. Inside the incubator.

Am beliebtesten
Scratch Assay & Wound Healing

Full wound closure kinetics — gap area every 5 minutes, automated t½ calculation, 24 conditions in parallel.

View protocol →
Cell Monitoring
Confluency & Proliferation

Continuous growth curves without manual counting. Automated alerts at defined confluency thresholds.

Finde mehr heraus ->
Drogentests
Cytotoxicity Time-Course

Real-time cell viability after drug addition. Capture onset, peak effect, and recovery — IC50 without endpoint assays.

Finde mehr heraus ->
3D-Modelle
Spheroid & Organoid Growth

Monitor 3D structure formation and growth over 14 days. Automated size and morphology tracking.

Finde mehr heraus ->
Quality Control
Contamination Detection

Morphology changes visible hours before contamination becomes critical. Remote alerts save experiments.

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High-Throughput
HTS Time-Lapse Screening

96 & 384-well time-lapse screening with XYZ stage add-on. Kinetic data across hundreds of conditions.

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Automated vs. Manual Time-Lapse

Why Automated Time-Lapse Wins

KriteriumzenCELL owl · AutomatedManual Microscopy
Imaging intervalEvery 5 minutes · continuousEvery 2–6 hours · manual
Incubator disruption✓ None — device stays inside✗ Every timepoint
Operator timeSetup once · runs unattendedPresent at every timepoint
Missed timepoints✓ Impossible✗ Nights / weekends / illness
Data consistency✓ Identical conditions every frame✗ Variable — different operators
Wells in parallel24 simultaneously1 at a time
Fernüberwachung✓ Any device, anywhere✗ Must be in lab
Output formatAVI · PNG · CSV · ImageJManual photos / inconsistent
FAQ

Time-Lapse Imaging — Häufig gestellte Fragen

What is the minimum imaging interval with zenCELL owl? +
The minimum imaging interval is 5 minutes per well. With 24 wells, the system captures one complete scan of all wells every 5 minutes continuously — generating up to 288 image sets per day per well. For longer experiments, intervals of 15–30 minutes are common.
How long can a time-lapse experiment run? +
Up to 14 days continuously without interruption. Storage is only limited by your PC hard drive — at 5-minute intervals over 14 days, typical storage requirements are 20–50 GB per experiment depending on image size settings.
Can I monitor the experiment remotely? +
Yes — zenCELL owl software provides remote access from any device via a web browser. You can view live images, check confluency curves, and receive automated alerts when defined thresholds are reached — from home, on weekends, or from another country.
What file formats does the time-lapse output? +
AVI time-lapse video (per well), PNG image stack for ImageJ analysis, and CSV kinetic data (confluency, gap area, or custom metrics vs. time). All formats are publication-ready and compatible with GraphPad Prism, Excel, and R.
Does time-lapse imaging affect cell health? +
No. zenCELL owl uses brightfield (transmitted light) imaging with a ~408 nm UV-A/visible LED light source at very low intensity. Cells remain inside the incubator at stable temperature and CO₂ throughout. Phototoxicity is not a concern for standard brightfield time-lapse experiments.

See Time-Lapse Cell Imaging Live

Watch zenCELL owl capture real cells in real time — scratch assay, confluency monitoring, spheroid growth — all in a free 20-minute MS Teams demo.

Buchen Sie Ihre kostenfreie Vorführung View Scratch Assay Protocol
zenCELL owl im Einsatz

Sehen Sie zenCELL Eule
Live – 30 Min.
- Kostenlos -

Echte Zellen. Echte Daten. Zellzählung mittels KI,
XYZ-Phase & komplette Software – live im Inkubator. Zweimal pro Woche über MS Teams.

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z. B. Konfluenzüberwachung, Scratch-Assay, Sphäroide...