Monitor cells under defined hypoxic conditions continuously — without breaking hypoxia, without opening the chamber, without disrupting your experiment. zenCELL owl connects via flat ribbon cable through any incubator door seal.
O₂ levels spike to atmospheric levels the moment the incubator door opens. Recovery takes 30–60 minutes. zenCELL owl eliminates every single chamber opening from your monitoring workflow.
The compact size and single flat ribbon USB-C cable make zenCELL owl straightforward to integrate into any hypoxic incubator — no reconfiguration required.
180×180×105mm, 1.5kg — fits on any standard shelf inside your hypoxic incubator without requiring reconfiguration.
The thin USB-C flat ribbon cable exits via the incubator cable feedthrough port, maintaining the sealed O₂-controlled environment.
Seal the chamber, set your target O₂ level (1–5%), start the experiment. zenCELL owl begins imaging immediately without warm-up.
Track confluence, morphology and cell count remotely, 24/7 — without ever opening the hypoxic chamber again during the experiment.
Incubator compatibility note: Most modern hypoxic incubators (Eppendorf Galaxy, Baker Ruskinn InVivo2, Thermo Scientific Heracell VIOS, Panasonic PHCbi) include a dedicated cable feedthrough port. The zenCELL owl flat ribbon USB-C cable fits through standard ports without compromising the sealed environment. For incubators without built-in feedthroughs, standard silicone cable grommets provide an equivalent seal. Contact us to verify compatibility with your specific model.
zenCELL owl is compact enough to fit inside any standard hypoxic incubator shelf. The flat ribbon USB-C cable passes through the door seal or cable feedthrough port — the only connection to the outside world. No heat generation, no oxygen consumption inside the chamber.
Any brightfield-detectable cellular process can be monitored under hypoxic conditions without disruption. zenCELL owl doesn't change the biology — it just lets you watch it continuously.
Data and power pass through the door seal via a thin flat ribbon cable. No significant gap, no O₂ leak. The hypoxic environment remains perfectly stable throughout the entire experiment.
No re-equilibration periods. No reoxygenation artefacts. No O₂ spikes in your data. True, uninterrupted hypoxic conditions from experiment start to finish.
Every 10 minutes, confluence and morphology data captured automatically. Compare hypoxic vs normoxic conditions. Track HIF pathway effects and oxygen-dependent growth changes over time.
Monitor 24 wells simultaneously — different O₂ levels, cell lines or drug treatments. All within the same sealed chamber, under identical environmental parameters.
Hypoxic monitoring critical for tumour biology, ischemia models and stem cell differentiation under low O₂. Continuous brightfield data without a single chamber opening.
Monitor from your PC, tablet or smartphone. Alerts when confluence thresholds are reached. No need to enter the hypoxic lab environment for routine monitoring checks.
Hypoxia is central to cancer biology, cardiovascular research, stem cell differentiation and wound healing. zenCELL owl provides continuous imaging across all these fields — without a single chamber opening.
Monitor how cancer cells adapt, migrate and proliferate under low O₂ conditions. Track morphological changes and epithelial–mesenchymal transition in real time without disruption.
Study cardiac and neural cell survival under ischemic stress. Monitor cell death kinetics continuously and capture recovery dynamics after reoxygenation without data gaps.
Hypoxia drives key stem cell differentiation pathways. Monitor morphological changes and confluence continuously without disturbing the hypoxic niche.
Run automated scratch assays under defined O₂ levels. Compare migration rates at 1%, 3% and 5% O₂ simultaneously — 24 conditions in one experiment.
Test drug efficacy under physiologically relevant O₂ levels. Many compounds behave differently in hypoxia versus normoxia. Capture this difference continuously across 24 wells.
Measure cytotoxicity in hypoxic conditions — track confluence loss and morphology changes under low O₂ in real time without endpoint assays or chamber disruption.
zenCELL owl is compatible with hypoxic chambers that feature cable feedthrough ports. The following models have been confirmed or are under validation.
See zenCELL owl running inside a hypoxic incubator live. Confirm compatibility with your specific model. On request via MS Teams.
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Get your free live online demonstration of the zenCELL owl directly inside an incubator, available twice per week.